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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
O00743
USC-OGP 2-DE database
:
O00743
O00743
General information about the entry
View entry in simple text format
Entry name
PPP6_HUMAN
Primary accession number
O00743
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit; Short=PP6C; EC=3.1.3.16; Contains: RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed;.
Gene name
Name=PPP6C
Synonyms=PPP6
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_5-6
{PLATELET 5-6}
Homo sapiens (Human)
map experimental info
PLATELET_5-6
MAP LOCATIONS:
SPOT OGP-0758
:
pI=5.51; Mw=32477
Cross-references
UniProtKB/Swiss-Prot
O00743; PPP6_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
PPP6_HUMAN
Primary accession number
O00743
Secondary accession number(s)
B2R5V6 B7Z2W9 B7Z5K9 Q5U0A2 Q9UIC9
Sequence was last modified on
July 1, 1997 (version 1)
Annotations were last modified on
March 15, 2017 (version 165)
Name and origin of the protein
Description
RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit; Short=PP6C; EC=3.1.3.16; Contains: RecName: Full=Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed;
Gene name
Name=PPP6C
Synonyms=PPP6
Encoded on
Name=PPP6C; Synonyms=PPP6
Keywords
Acetylation
;
Alternative splicing
;
Cell cycle
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Hydrolase
;
Manganese
;
Metal-binding
;
Protein phosphatase
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X92972; CAA63549.1
; -; mRNA
EMBL
AF035158; AAD45400.2
; -; mRNA
EMBL
AK295190; BAH12005.1
; -; mRNA
EMBL
AK299087; BAH12945.1
; -; mRNA
EMBL
AK312332; BAG35253.1
; -; mRNA
EMBL
BT019708; AAV38514.1
; -; mRNA
EMBL
AL445930; CAI13677.1
; -; Genomic_DNA
EMBL
CH471090; EAW87611.1
; -; Genomic_DNA
EMBL
BC006990; AAH06990.1
; -; mRNA
CCDS
CCDS48018.1; -. [O00743-3]
; .
CCDS
CCDS48019.1; -. [O00743-2]
; .
CCDS
CCDS6861.1; -. [O00743-1]
; .
RefSeq
NP_001116827.1; NM_001123355.1. [O00743-3]
; .
RefSeq
NP_001116841.1; NM_001123369.1. [O00743-2]
; .
RefSeq
NP_002712.1; NM_002721.4. [O00743-1]
; .
UniGene
Hs.744091; -
; .
ProteinModelPortal
O00743; -
; .
SMR
O00743; -
; .
BioGrid
111529; 50
; .
DIP
DIP-27581N; -
; .
IntAct
O00743; 37
; .
MINT
MINT-1139697; -
; .
DEPOD
O00743; -
; .
iPTMnet
O00743; -
; .
PhosphoSitePlus
O00743; -
; .
BioMuta
PPP6C; -
; .
OGP
O00743; -
; .
EPD
O00743; -
; .
MaxQB
O00743; -
; .
PeptideAtlas
O00743; -
; .
PRIDE
O00743; -
; .
DNASU
5537; -
; .
Ensembl
ENST00000373547; ENSP00000362648
; ENSG00000119414. [O00743-1]; .
Ensembl
ENST00000415905; ENSP00000411744
; ENSG00000119414. [O00743-2]; .
Ensembl
ENST00000451402; ENSP00000392147
; ENSG00000119414. [O00743-3]; .
GeneID
5537; -
; .
KEGG
hsa:5537; -
; .
UCSC
uc004bpg.5; human. [O00743-1]
; .
CTD
5537; -
; .
DisGeNET
5537; -
; .
GeneCards
PPP6C; -
; .
HGNC
HGNC:9323; PPP6C
; .
HPA
HPA050940; -
; .
MIM
612725; gene
; .
neXtProt
NX_O00743; -
; .
OpenTargets
ENSG00000119414; -
; .
PharmGKB
PA33687; -
; .
GeneTree
ENSGT00550000074961; -
; .
HOGENOM
HOG000172696; -
; .
HOVERGEN
HBG000216; -
; .
InParanoid
O00743; -
; .
KO
K15498; -
; .
OMA
WITWASE; -
; .
OrthoDB
EOG091G0B6S; -
; .
PhylomeDB
O00743; -
; .
TreeFam
TF105563; -
; .
Reactome
R-HSA-204005; COPII (Coat Protein 2) Mediated Vesicle Transport
; .
SIGNOR
O00743; -
; .
ChiTaRS
PPP6C; human
; .
GeneWiki
PPP6C; -
; .
GenomeRNAi
5537; -
; .
PRO
PR:O00743; -
; .
Proteomes
UP000005640; Chromosome 9
; .
Bgee
ENSG00000119414; -
; .
CleanEx
HS_PPP6C; -
; .
ExpressionAtlas
O00743; baseline and differential
; .
Genevisible
O00743; HS
; .
GO
GO:0005829; C:cytosol
; IDA:MGI; .
GO
GO:0000139; C:Golgi membrane
; IEA:GOC; .
GO
GO:0046872; F:metal ion binding
; IEA:UniProtKB-KW; .
GO
GO:0004722; F:protein serine/threonine phosphatase activity
; IDA:MGI; .
GO
GO:0048208; P:COPII vesicle coating
; TAS:Reactome; .
GO
GO:0000082; P:G1/S transition of mitotic cell cycle
; TAS:ProtInc; .
GO
GO:0006470; P:protein dephosphorylation
; IDA:MGI; .
Gene3D
3.60.21.10; -
; 1; .
InterPro
IPR004843; Calcineurin-like_PHP_ApaH
; .
InterPro
IPR029052; Metallo-depent_PP-like
; .
InterPro
IPR006186; Ser/Thr-sp_prot-phosphatase
; .
Pfam
PF00149; Metallophos
; 1; .
PRINTS
PR00114; STPHPHTASE
; .
SMART
SM00156; PP2Ac
; 1; .
SUPFAM
SSF56300; SSF56300
; 1; .
PROSITE
PS00125; SER_THR_PHOSPHATASE
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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